What Do The Results Mean?
|Autoantibody Negative||The risk of developing type 1 diabetes in the near future is very low. However there is no guarantee that an individual will not develop autoantibodies in the future. Since autoantibody status can change over time, especially in children with maturing immune systems, we offer screening annually up to 18 years of age.|
|Positive for 1 Autoantibody||Overall the risk of developing diabetes is low (about 25% in the next 5 to 10 years). Such individuals may be eligible for additional testing and to be rescreened and have a HbA1c checked every 12 months.|
|Positive for 2+ Autoantibodies||People who test positive for 2 or more autoantibodies are at significantly increased risk of developing type 1 diabetes. We offer further testing to better assess this risk and closer follow up if desired.|
How Are Participants Notified of Results?
Persons with negative diabetes-related autoantibody test results will receive a letter in the mail in 4 to 6 weeks. Of the people that are screened, 95% of participants test negative. If the test comes back positive for one or more autoantibodies, notification is made via phone call from a member of the study team. We will explain which autoantibody(ies) were detected and what options are available for continued monitoring in the study or if there is an applicable prevention trial that may be of interest.